Priscilla Van Wynsberghe - Colgate University - Faculty Directory
Priscilla Van Wynsberghe

Priscilla Van Wynsberghe

Assistant Professor of Biology
Biology, 211 Olin Hall
p 315-228-6480


BA, Ohio Wesleyan University, 2001; PhD, University of Wisconsin-Madison, 2007

Teaching Experience

Howard Hughes Medical Institute Teaching Fellow, University of Wisconsin-Madison 2005-2006;
Teaching Assistant, University of Wisconsin-Madison 2002-2003


Microbiology, Genetics, Molecular Biology, RNA biology, Women's Biology


Understanding how small RNAs called microRNAs, and the proteins that control microRNAs regulate somatic and germ line development in the nematode C. elegans.


  • 2Van Wynsberghe, P. M. and A.E. Pasquinelli. 2014. Period homolog LIN-42 regulates miRNA transcription to impact developmental timing. Worm. 3:e974453.
  • 2Van Wynsberghe, P. M., E.F., Finnegan, T. Stark, E.P. Angelus*, K.E. Homan*, G.W. Yeo, and A.E. Pasquinelli2. 2014. The period protein homolog LIN-42 negatively regulates microRNA biogenesis in C. elegans. Dev. Biol. 390:126-35.
  • Gimenez-Barcons, M., I. Alves-Rodrigues, J. Jungfleisch, P.M. Van Wynsberghe, P. Ahlquist, and J. Diez. 2013. The cellular decapping activators Lsm1, Pat1, and Dhh1 control the ratio of subgenomic to genomic flock house virus RNAs. J. Virol. 87:6192-200.
  • Van Wynsberghe, P. M., and E. M. Maine. 2013. Epigenetic control of germline development. In “Advances in Experimental Medicine and Biology - Germ Cell Development in C. elegans” (T. Schedl, Ed.), Springer Science, New York. 757:373-403.
  • 1Van Wynsberghe, P. M., 1S. P. Chan, F. J. Slack, and A. E. Pasquinelli. 2011. Analysis of microRNA expression and function. In “Methods in Cell Biology – Caenorhabditis elegans” (J. H. Rothman, Ed.), Elsevier Inc., San Diego. 106:219-52.
  • Van Wynsberghe, P. M., Z. S. Kai, K. B. Massirer, V. H. Burton, G. W. Yeo, and A. E. Pasquinelli. 2011. LIN-28 co-transcriptionally binds primary let-7 to regulate miRNA maturation in Caenorhabditis elegans. Nat. Struct. Mol. Biol. 18:302-8.
  • 1Bracht, J. R., 1P. M. Van Wynsberghe, V. Mondol, and A. E. Pasquinelli. 2010. Regulation of lin-4 miRNA expression, organismal growth and development by a conserved RNA binding protein in C. elegans. Dev. Biol. 348:210-21.
  • Van Wynsberghe, P. M. and P. Ahlquist. 2009. 5’ cis-elements direct nodavirus RNA1 recruitment to mitochondrial sites of replication complex formation. J. Virol. 83:2976-88.
  •  Van Wynsberghe, P. M., H. R. Chen, and P. Ahlquist. 2007. Nodavirus RNA replication protein A induces membrane association of genomic RNA. J. Virol. 81:4633-44.
1 co-first authors
2 corresponding author
* Colgate University Undergraduate

Professional Experience

Postdoctoral Fellow, University of California at San Diego, 2007-2010; Postdoctoral Fellow, Syracuse University, 2010-2011


  • NIH NRSA Postdoctoral Fellowship 2009-2011
  • HHMI Teaching Fellow 2005-2006
  • HHMI Predoctoral Fellowship 2001-2006
  • Phi Beta Kappa 2001
  • Sigma Xi Student Research Award 2001